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July 31, 2007

Illegally importing prescription drugs

Filed under: Adderall — Anthony @ 4:53 am

As you might know, if you’ve read the first couple posts in the Adderall category, Adderall is actually a second choice alternative. What I really want is provigil – a new-ish drug that has all of the wakefullness promoting effects of Adderall, without any of the amphetamine side effects. In particular – it does not effect one’s ability to go to sleep when one wants to go to sleep – my primary issue with Adderall right now.

For some reason, however, getting insurance to cover Provigil is nearly impossible without a battery of specialist appointments and sleep studies and such. Without insurance, it’s at least a couple hundred dollars a month for the smallest dose.

Generics are not – and will not – be available for a few years at least.

This raises some disturbing questions about the nature of pharmaceutical industry. The current system encourages the development of drugs, then makes it absolutely unafordable to the majority of people who need it. It’s maddening enough for me; I can’t imagine how it must be for people with truely debilitating diseases who end up spending thousands a month on prescription drugs… or simply going without.

The drug companies put a lot of money up front, take a lot of financial risk, and create something truely valuable. Obviously, they SHOULD be rewarded. But to the point of selling their product, marked up literally thousands of percent, for 20 years (or whatever the drug patent duration is) before other companies are allowed to compete? I honestly can’t understand how the CEO’s of these companies get any sleep.

Back to Provigil; I was recently looking for some information on when generics would be available, and came across a discussion forum with the topic of “the best out-of-country internet pharmacy to purchase generic modafinil?” (Modafinil being the active ingredient in Provigil). I looked at a couple of sites mentioned in that thread – “pharmacies” in Europe, India and other more or less exotic places. Most were pretty shady/scammy looking, but not all of them. They all, however, did have about the same procedure for buying medicine; fill out a form and pay with a credit card, and they will have a hired physician look at it and write a prescription, then ship it to you in a discreet envelope.

I found Modalert, Alertec and some others (Provigil generics in India, Canada and other regions, respectively), for as little as $30/month. They are manufactured buy reputable sources, and many people have great luck with them. Of course there is always the concern of buying drugs from less regulated countries – indeed, there are many people who bought drugs from online sources and simply never got the product, or received caffeine pills, amphetamines – or in some cases, something that did absolutely nothing but cause nasusea and who knows what else. But there are people who have been buying from the same source for years without a qualm, and have had no problems.

Of course the one other major hurtle is the legal implications of importing controlled substances. If I remember correctly, for importing a schedule IV controlled substance like modafinil, you can get a maximum of 5 years in prison. BUT – it is extremely rare that drugs coming into the country are detected, and if they are – it’s extremely rare for anyone to be prosecuted (unless it’s a very large amount of something).

The bottom line? There are options for those who’s potential benefits from importing drugs outweigh the potential costs.

Personally, regarding Provigil, the benefit is not worth the potential cost; being poisoned by tainted drugs, jail time, etc – but it’s nice to know that if I’m in a true state of misery that an immorally expensive drug could alleviate – there are options that I’d be perfectly willing to pursue.

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July 30, 2007

Negativity

Filed under: Blogorrhoea, Uncategorized — Anthony @ 7:26 pm

Simon and Paula. The evening news. The office talk around the water cooler. The family gossip over the dinner table.

When you step back and observe – it’s amazing how our brains thrive on negativity. I find myself doing it – sometimes in subtle ways, sometimes in very blatant ways. When I’m reading movie reviews, I am completely uninterested in the “A” and “B” reviews. No, I go for the D’s and F’s. Why? I don’t know. For some reason, it’s much more “exciting” to read the harsh, scathing reviews. Some days, here at work, I find myself wanting confrontation. If there’s a chance of confrontation because someone is being a jerk, I’m perfectly willing – hoping – they push the right button so I’ll have an excuse for an unpleasant blow-up.

Why? Why are people like that? Is it culture? Is it universal?

I’ve been sitting here listening to an employee conversation from my office, that has continued for about 20 minutes now (boss is on vacation). The topics have spanned everything from the way the business is run to the owner’s relative’s personal lives; the latest irritating client to… you name it. It has turned into a festering whine session.

If I wasn’t here today, I have no doubt I’d be fair game for the conversation. EVERYone is fair game BY everyone… nearly everyone anyway. There is only one fellow here does not regularily take part in these conversations, and often actually steers the conversation away from negativity.

I want to be like him when I grow up. :D

Negativity acomplishes absolutely nothing.

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July 26, 2007

Smoking in Movies?

Filed under: Blogorrhoea, Uncategorized — Anthony @ 4:42 am

There’s this little oddball topic that bothers me occasionally. Occasionally as in… hmmmm, every other Friday night on average, around 8:00 pm or so.

I was reminded of this topic tonight when I saw this news article on Disney banning smoking in movies. Usually, the only time I remember the topic at all is on Friday night…

See, by 8:00 pm or so, we are usually into the meat of our Friday Night Movie. We’ve finished our pizza and hotwings and soda, gotten a feel for the plot, gotten to know the characters – etc. We’ve put the kiddo in bed, snuggled up a bit, and settled in for the duration of the movie.

ANYway, I will hold you in suspense no longer. What is the little oddball topic?

To smoke in a movie is akin to … gosh, I dunno, something really bad. It’s a no-no. Cigarettes are deadly, right? What are we teaching the viewers? KIDS MIGHT BE WATCHING, FOR CRYING OUT LOUD!

So, they do away with the cigarettes and all is good. Everyone is happy. So happy that we celebrate over a nice glass of scotch. Or maybe a nice beafeater gin. That’s a weird name, but apparently as gins go, it’s good stuff. Or maybe a 6-pack good ole’ beer. Or a martini? Vodka on the rocks? I don’t even know what that means, but I’m pretty sure that’s what heros like. Movie heros, that is.

Ok, seriously now – literally two of every three movies we watch have hard liquor. Not R-rated movies, mind you; for the most part, we maintain PG-13 and below. Every movie with a slightly depressed person – where are they at night? The bar of course. Every tough guy who’s lost a wife or had some trial – the bar. Every business partner – meeting some bigwig? Well of COURSE he’s going to pour you somethin’… something clear, preferably. It’s classier if it’s clear.

Now, don’t get me wrong – I’m not yelling (in THIS post) at anyone for writing alcohol consumption into movies. Maybe they need to be yelled at – that’s not what this post is about. What DOES intrigue me is how culture and media latched onto smoking as such a critical issue, while other glaring issues flourish, unabated. Alcohol is only one, and it’s the one I’m talking about simply because it’s directly comparable to smoking.

I’m no scientist, but it seems to me alcohol is at LEAST as dangerous as smoking. Yes, smoking tends to kill a person. What effect does unrestrained alcohol consumption have? It doesn’t always kill the person. No. It just kills the person sometimes, tears the family apart, shrinks the brain, harms fetuses, occasionally kills the driver of the other car, etc.

Ok, RANT OVER!

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July 20, 2007

Random Reflections – ADD/ADHD

Filed under: Health — Anthony @ 3:11 pm

ADD – does it “exist?”I’ve never really given much thought to ADD; I never had any reason to. I’ve heard various opinions touted (and spouted), but never really formed one of my own.That has changed, however, due to a couple of vaguely related circumstances in my life. One is having been prescribed Adderall (THE major current topic of this blog), and the other – which I haven’t said much about – is Zoloft.

But before I go into how those two drugs sparked an interest in the ADD debate, I’m simply going to spill my opinion. Before you get irritated with me, please read the whole post!

I believe that ADD/ADHD as a sickness/handicap does NOT exist intrinsically in the brain. I believe ADD/ADHD is social/cultural flaw.

Please note the “intrinsically” in there. What I mean is – ADD/ADHD is something, but I do not believe it is a “problem” with the brain; I believe it is a problem with our culture.People have varying abilities in differing areas. Some are naturally good at math. Some are good at sports. Some have the ability to take a visual “snapshot,” and involuntarily retain it well enough to refer back to the image for previously unnoticed information (aka “photographic memory – wish I had one). Some can spell (and I’m not one of them). Some are creative and are able to synthesize new ideas apparently out of thin air. Some, who may not be as creative, have the ability to spend large amounts of time on mundane tasks without feeling bored.Yes, I was trying to be sneaky with those last two examples; they are how I perceive the extremes of ADD vs. non-ADD. one extreme (ADD), you have those people who’s minds bounce rapidly from one idea to the next, so overflowing with creativity that they rarely finish what they start, because there’s always something new just around the corner. On the other extreme, you have the “machine” – the staple of society that gets things done. The person who can focus relentlessly on a tedious task until it’s done.

There is nothing inherently “better” or “worse” about either extreme, provided society has not formed a skewed perspective of what is “normal” – and therein, I believe, lies the true cause of ADD.

Society has created ”ADD” as a “problem” by trying to fit everyone into the same “normal” shoe size, regardless of their natural shoe size. Our society emphasizes behaviors that maximize effectiveness in a very limited range of circumstances. The whole idea of school being a place you go to sit at desks and learn from textbooks for so many hours per day is, if you really step back and look at the big picture, totally arbitrary (the VERY big picture – think of it in terms of evolution). (By the way, sorry to interrupt, but I have to mention – I don’t necessarily “believe” in evolution, but it is frequently a useful way to think about things – I’ll write a post on that someday…). Sitting in an office for 8 hours a day working for a wage is also totally arbitrary.

“Arbitrary” does not mean “bad” – but it does become a problem when people forget that these ingrained “traditions” are, in fact, arbitrary.

The point being – the academic and professional worlds tend to favor those on the non-creative side of things. Therefore, anyone NOT of the non-creative group are not optimized for our society. Really, I SHOULD say “our society is not optimized for that group of people.” 

I’ll summarize a bit before continuing: society is set up in such a way to maximize the effectiveness of non-ADD people, and as such, creates a problem for those people labeled with ”ADD.”

Is it possible to envision a society that maximizes both brain types equally? Having grown up in my society (duh), it is hard to envision. But if I “zoom out” of my limited range of experience; if I zoom out to that evolutionary perspective I mentioned previously – it becomes a bit easier to imagine societies that do not favor non-ADD’ers. THAT, however, is a mental exercise I’ll save for another post. :D

Anyway, say we did have a society that favored ADD’ers. What would the “handicap” be called that prevented “focusers” from flourishing? ASD – “Attention Surplus Disorder?” “Lack Of Creativity Disorder?”

This brings me to the crux of the issue in my mind: Should those ASD’ers be medicated to help them be more creative, and less fixated on tedious tasks?

My opinion is - it is absolutely, perfectly ethical to allow people to medicate themselves to allow maximum HES (happiness, effectiveness, survivability) in any circumstance they find themselves stuck in, insomuch as those circumstances have created their inability to be HES. What do I mean by that? I believe it is ethical to treat the “abnormal” to bring them up to “par” with the “normal” – but obviously no further. This issue obviously gets hairy when a minority group of students in some college class takes Adderall to perform better on a test, and in doing so, skews the curve, harming those who didn’t medicate. But that is another topic.

There is one other caveat to my opinion that you may have noticed – while I believe people should be able to medicate themselves without stigma or being stamped with a disorder, I do not have an opinion (yet) on the medication of children. One thing I DO know, is that I’m most assuredly uncomfortable hearing about doctors and parents giving their 6 year old kids amphetamines. Adderall is such a powerful drug, with so much potential for abuse and dependence, if not addiction, that my gut reaction to giving it to little kids is… well, uncomfortable. Is it ethical? Again, I don’t know; I don’t have an opinion on that, and probably won’t until I happen to have a child with ADD. For now, I’m going to claim ignorance and naivety, and plea the 5th. :)

To summarize again – I do not believe ADD is a disorder, but I do believe it is a problem. It is not a problem with an individual; it is a problem with society. Because individuals with ADD have no choice about the current state of society, I believe it is perfectly reasonable to medicate, and that those who do medicate should be able to do so without fear of stigma.

Now, going waaaaay back, all the way to the top of this post, I mentioned that my experiences with Zoloft and Adderall initiated my interest in ADD. Really, it initiated interest in mental issues and synthetic chemical treatments in general.

I used to be very uncomfortable taking Zoloft. It made me feel like I was inadequate as a human. I  felt like I just happened to be born at the right time… and a crutch was available. I felt like I was cheating somehow. If I couldn’t make it 100 years ago, before Zoloft or any other anti-depressants were available, I shouldn’t be able to make it now.

Let me tell ya – those thoughts don’t do anything good for one’s self-esteem.

The turning point came for me when I, for some reason I don’t remember, shared my issues with a co-worker. I told him about my use of Zoloft, and my difficulty coping without it.

His response left me … irritated.

I don’t remember it exactly, but it was some blanket statement to the effect of:

“I hate how people drug themselves these days. They completely ignore the real problem. They need to get things right in their lives, and get over it.”

That may actually be the case for some people, whose depression is rooted in current and past circumstances rather than an actual biological issue in the brain. For those people, maybe they do need to address issues in their lives, instead of applying a “Band-Aid.” But to throw that blanket over everyone who takes anti-depressants (or any other chemical) is the epitome of naivety. It is unadulterated ignorance. I don’t know if chemical imbalances existed 100 years ago… for all I know, they’re the result of a single, widely used pesticide. I have no idea.

What I do know is that humans have always used the latest tools they have available, and it’s ludicrous to think of that as a “weakness.” I’m not going to get rid of my car because they didn’t have cars 10,000 years ago.

For me personally, depression comes and goes arbitrarily, regardless of circumstances. It manifests in the form of total lack of motivation to do participate in life, whether that be social engagements or paying the bills. It brings irrational thoughts and desires with it – extreme negativity, the impulse to harm myself physically, etc. There is no rhyme or reason to it.

Facing that external and internal stigma in my own life caused me to evaluate some of my own “blanket” assumptions. ADD in particular happens to be something I’ve thought a lot about because of my recent use of Adderall, and ADD’s general prevalence in our society.

[note: I was interrupted from finishing this post, and being of fickle inspiration, could not get back into it. So without carefully checking and reorganizing it, I simply decided to post it as it "as was", unedited and unfinished. Thus the abrupt ending! I'm sorry!]

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